Few signs and symptoms that you have a liver disease

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Few signs and symptoms that you have a liver disease

Few signs and symptoms that you have a liver disease

Few signs and symptoms that you can develop if you have a liver disease.


Your liver does a lot of things to keep you healthy. It is especially important as it acts as your body’s filter to clear out toxins. This include clearing the blood of drugs and other poisonous substances such as ammonia. Liver produces bile, which helps to carry away waste products and breaks down fats in the gut during digestion. It also produces certain proteins for blood plasma and other important molecules such as cholesterol which are especially important for transport of vital nutrients throughout the body. The proteins that are produced by the liver play numerous important roles in our body. Additionally, but equally important is its role in maintaining our body’s energy level in the form of glucose. It converts excess glucose into glycogen for storage – this glycogen can later be converted back to glucose for energy. This is important for our body’s survival and helps us beat hunger and stay active for extended periods of time. You may not know it but – the liver has an important role in resisting infections also. Some factors like heavy consumption of alcohol, chronic viral infections, eating an unhealthy diet for too long or overdose of commonly prescribed medications can cause liver damage other factors that may increase your chances of getting disease include:


  • Obesity
  • Type 2 diabetes
  • Tattoos or body piercings
  • Drug abuse
  • Exposure to other people’s blood and body fluids
  • Unprotected sex
  • Exposure to certain chemicals or toxins
  • & a family history of liver disease


When some of these risk factors are present – your liver may get stressed out. This will lead to liver injury which can present with various peculiar yet vague signs and symptoms. According to experts – very few people actually know when their liver is failing, this is because most of the people aren’t even aware of what causes liver failure and even lesser people know how to lookout for the symptoms. So, let’s take a look at four common signs and symptoms of liver injury or liver failure. If you see one or more of these signs – you should immediately consult a medical professional to rule out any underlying disease.


1-loss of appetite
A disinterest in food, loss of appetite and weight loss are some early symptoms of liver problems.


2- Fluid retention fluid retention is also one of the most common sign of liver disease. It appears in more than 50 percent of the people who have cirrhosis, a condition in which scar tissue replaces healthy liver tissues accumulating fluid may cause distension of your abdomen also known as ascites or may lead to swelling in your legs also known as edema. This happens because due to long term liver disease – high blood pressure develops in your liver veins. This also happens when your liver is unable to make albumin – a protein that prevents leakage of fluid from your bloodstream into the adjoining tissues. Both of these factors lead to eventual fluid leakage from your blood vessels and fluid accumulation into your abdomen or under your skin. Treatment options for fluid retention include a low-sodium diet which helps to treat mild fluid retention. For moderate-to-severe fluid retention, your doctor may prescribe certain medications k/a diuretics which help in removing the excess fluid from your body by increasing your urine output. But in some severe cases– your doctor can advise a procedure known as paracentesis. Using a needle doctors perform paracentesis to drain the excess abdominal fluid which leads to temporary but instant relief.


  1. Jaundice jaundice is a condition that causes darker urine and a yellowish tint in your skin. It can also lead to yellowing of the whites of your eyes aka “sclera”. It appears when bilirubin, builds up in your bloodstream. Bilirubin is a pigment that forms when red blood cells break down. Usually – a healthy liver absorbs bilirubin and converts it into bile. This bile is then excreted by your body with your stools, but a diseased liver is unable to do so. Hence yellowish bilirubin accumulates in your body and causes yellowish discoloration of skin, eyes and urine. You may ask what the treatment options of jaundice are. Well that basically depends upon the reason why jaundice has developed in the first place and there can be a wide variety of reasons. Your doctor will evaluate you by performing different types of tests like a complete blood count (cbc), liver function tests (lfts), ultrasonography of the liver and liver biopsy, if needed.


  1. Increased tendency of bleeding a healthy liver produces clotting factors which are basically proteins that are activated whenever you are injured. These proteins lead to formation of a blood clot which stops the bleeding. An unhealthy liver leads to a decrease in the production of these clotting factors, which ultimately results in an increased tendency to bleed, so whenever you are injured, it takes a longer time for your body to stop the bleeding. You may also experience bruises under your skin with minor trauma. Patients with advanced liver disease such as liver failure have very low levels of these clotting factors and can experience episodes of spontaneous bleeding without any injury. These patients may bleed into their stomach which results in blood in their vomit, or they can even experience bleeding in their lungs which results in blood during coughing. Liver cirrhosis leads to an enlarged spleen k/a splenomegaly. Our spleen has the job of collecting platelets from our bloodstream and their storage. When spleen gets enlarged excessive amounts of platelets are removed by the spleen from our blood. This phenomenon is k/a splenic sequestration. This may lead to a very low platelet count that makes you more susceptible to nose bleeds and bleeding gums.


  1. Confusion your liver is the major purifier of toxins from your blood, and it also metabolizes a lot of chemicals we ingest – such as those present in foods and medicines. When your liver is unable to filter these toxins, they may travel and accumulate in your brain. The resulting condition, known as hepatic encephalopathy, can cause confusion, memory problems, lethargy and in later stages even coma.


  1. Frequent nausea and vomiting this also results due to the Organ inability to remove toxins from our blood which slowly build up and trigger certain areas in our brain that results in nausea and vomiting.

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Wickham Laboratories Ltd is a GMP/GLP compliant laboratory with over 50 years of global experience in specialized pharmaceutical and medical device testing in the fields of microbiology and toxicology. We are a distinctive company, with customer relationship skills that set us apart. Here at Wickham Laboratories, you can be assured of a reliable, confidential and cost-effective extension to your in-house capabilities. Conducting business with clients worldwide, we have the capability to offer solutions to microbiology development projects from early-stage to product release as well as routine product testing and toxicology services.

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